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VOL. 11, ISSUE 2 (2026)
Gene editing-based sterility in zebrafish: implications for aquaculture and environmental safety
Authors
Korhale G A
Abstract
The rapid expansion of aquaculture has raised concerns regarding
uncontrolled breeding and ecological risks associated with the escape of farmed
fish into natural ecosystems. Sterility induction in fish has emerged as an
effective strategy to prevent genetic contamination and improve production
efficiency. This study investigates gene editing–based approaches for inducing
sterility in zebrafish (Danio rerio), focusing on genes involved in germ
cell development and gonadal differentiation. CRISPR-based gene editing
techniques were employed to disrupt key reproductive genes, leading to impaired
germ cell formation and reduced fertility. Molecular and phenotypic analyses
confirmed successful gene disruption, resulting in altered gonadal structure
without affecting somatic growth. The findings demonstrate that gene editing
provides a precise and efficient method for producing sterile fish. The study
highlights the potential applications of sterile fish in aquaculture to enhance
biosafety, prevent ecological imbalance, and improve feed conversion
efficiency. However, ethical considerations, regulatory challenges, and
long-term ecological impacts must be addressed before large-scale
implementation.
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Pages:52-55
How to cite this article:
Korhale G A "Gene editing-based sterility in zebrafish: implications for aquaculture and environmental safety". International Journal of Zoology Studies, Vol 11, Issue 2, 2026, Pages 52-55
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