ARCHIVES
VOL. 10, ISSUE 2 (2025)
The medicinal legacy of leeches: Historical roots and therapeutic perspective
Authors
Marina G D’Souza, Vivek V Byahatti, Shankar Yelmame, Srinivas Nandyala, Laxmikant B
Abstract
Leeches have played a significant role in medicine for centuries, with
their therapeutic applications dating back to ancient civilizations such as
those of Egypt, Greece, and India. Historically, associated with bloodletting,
leeches were believed to restore balance to the body’s humors. In modern
medicine, their role has evolved significantly, supported by scientific
validation. Leech therapy, or Hirudotherapy, has become a keystone in various
medical fields, particularly in microsurgery and reconstructive procedures.
Their ability to alleviate venous congestion is invaluable in grafts,
reattachment surgeries, and plastic surgery, where their anticoagulant saliva
helps restore blood flow, preventing tissue necrosis. The medicinal efficacy of
leeches lies in their saliva, which contains a variety of bioactive compounds;
Hirudin, a potent anticoagulant, prevents clot formation, while Calin inhibits
platelet aggregation, ensuring prolonged bleeding and improved venous drainage.
Additional components like Hyaluronidase enhance tissue permeability, and
Bdellins provide anti-inflammatory effects, broadening their therapeutic
potential. Beyond surgical applications, leeches have been successfully used in
the management of osteoarthritis, offering pain relief and reducing
inflammation, as well as in treating conditions such as varicose veins and
hemorrhoids. The medicinal legacy of leeches highlights the seamless connection
between ancient wisdom and modern science, providing a foundation for innovative
therapeutic strategies in contemporary medicine. This article explores the
historical roots of leech therapy, highlights its transition from traditional
practice to scientifically supported medicine, and provides insights into
specific applications in conventional healthcare.
Download
Pages:24-27
How to cite this article:
Marina G D’Souza, Vivek V Byahatti, Shankar Yelmame, Srinivas Nandyala, Laxmikant B "The medicinal legacy of leeches: Historical roots and therapeutic perspective". International Journal of Zoology Studies, Vol 10, Issue 2, 2025, Pages 24-27
Download Author Certificate
Please enter the email address corresponding to this article submission to download your certificate.