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VOL. 8, ISSUE 4 (2023)
Evaluation of fish oil impacts on hepatic structure in male rats
Authors
Rana A Alzahrani
Abstract
This study aimed to evaluate the protective impacts of fish oil on lead
acetate induced toxicity of liver in rats. Forty male rats were randomly
divided to four sets, each of them contained of ten rats. Control male rats
received normal saline solution, whilst treated rats received lead acetate (150
mg/kg body weight) three times a week, fish oil and lead acetate (650 mg/kg
body weight/day), and the last group received fish oil (650 mg/kg body
weight/day) for six weeks by sterile tube. The results illustrated an
insignificant increase in average liver weight with greatest and least liver
weight gained was of 10.49±1.51g and 9.76±2.09 g respectively. on the other
hands, the hepatic histology of rats treated with fish oil showed slight
alteration such as; congestion around central vein. Also, the results of
present study revealed that fish oil have been starting the positive effect on
hepatic normal structure in lead acetate treated male rats which could be
attributed to presence of antioxidants that reduce oxidative stress.
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Pages:23-27
How to cite this article:
Rana A Alzahrani "Evaluation of fish oil impacts on hepatic structure in male rats". International Journal of Zoology Studies, Vol 8, Issue 4, 2023, Pages 23-27
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