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VOL. 8, ISSUE 3 (2023)
Role of blood cells in HIV-TB Co infection epidemiology diagnosis and management
Authors
Dr. Chandra Anjaiah
Abstract
HIV/AIDS pandemic has caused a resurgence of TB, resulting in increased
morbidity and mortality worldwide. HIV and Mycobacterium tuberculosis have a
synergistic interaction; each accentuates progression of the other. Clinical
presentation of TB in early HIV infection resembles that observed in immune competent
persons. In late HIV infection, however, TB is often atypical in presentation,
frequently causing extrapulmonary disease. These factors coupled with low
sputum smear-positivity, often result in a delayed diagnosis. HIV-infected
patients respond well to the standard 6-month antituberculosis treatment
regimens, although mortality is high. Antituberculosis treatment is complicated
by frequent drug-interactions with highly active antiretroviral therapy (HAART)
and adverse drug reactions are more common among HIV-infected patients.
Guidelines for the management of patients co-infected with HIV and TB are still
evolving. Timely institution of antituberculosis treatment using the directly
observed treatment, short-course (DOTS) strategy and HAART markedly improves
the outcome of HIV-infected patients with TB.
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Pages:83-88
How to cite this article:
Dr. Chandra Anjaiah "Role of blood cells in HIV-TB Co infection epidemiology diagnosis and management". International Journal of Zoology Studies, Vol 8, Issue 3, 2023, Pages 83-88
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