International Journal of Zoology Studies

Authors
Mahasweta Chatterjee, Gobinda Chandra Sadhukhan, Jayanta Kumar Kundu

Abstract
Enormous work has been done in the field of heavy metal toxicity till date. Maximum works were carried out to see the effects of arsenic and lead because of their huge applications by different industries. But, the factory effluents also contain some other metals including cadmium. Cadmium contaminates our environment not only through water but also through air and food. Works have already been performed to see the adverse effects of cadmium on environment as well as on different animal bodies; but, very few attempts were made to find remedies of such problems. Being carcinogenic, these metals can produce severe toxicity to various organs including liver, lung, kidney, testis etc. by interfering with normal cellular mechanisms. Remedies with different chemicals and radiotherapy treatments give some relives but add on different side effects. Research shows that the antioxidant pool present in some herbal extracts and homeopathic tinctures have anti-toxic, anti-oxidative and anti-carcinogenic properties which help them to fight against such toxic environment. the present study was undertaken to see the adverse effects of cadmium on different mammalian organs and the remedial effects of two common herbs, the Phyllanthus emblica (amla) extract and Lycopodium clavatum (club moss) in its homeopathic tincture form (Lycopodium 200C). To conduct this study Swiss albino mice were used as experimental model and different biomarker enzymes and biomonitoring protein molecules were selected to detect their total content as well as activities; these are serum alkaline phosphatase, serum lactate dehydrogenase, tissue metallothionein, serum urea nitrogen and creatinine etc. Results showed drastic changes with the applications of cadmium in different parameters which are again recovered by the applications of amla extract and Lycopodium 200C.