A comparative study on the content of Protein, moisture, ash and fat four Indian fishes Schizothorax plagiostomus, Cyprinus carpio specularis, Cyprinus carpio communis, Catla-catla were carried out in the present study. The proximate analysis revealed that the protein content of Schizothorax plagiostomus, Cyprinus carpio specularis, Cyprinus carpio communis, Catla-catla 15.51%,13.93%,16.9%,18.79% (% of wet weight), respectively. The total fat content was generally high, ranging from 3.58% to 19.56 % and ash ranged from 1.31% to 2.8 %. Moisture content varies from 78.06% to 65.83%. This result evidently shows that the importance of fish nutrition in the human diet for fighting the diseases like heart problems, cholesterol and many growth-related problems.