Histopathological studies for diagnosis of indeterminate leprosy in Uttar Pradesh, India
Dr. Archana Singh
Leprosy is one of the oldest human bacterial disease recognized by a Norwegian scientist Armauer Hansen working in Bergen in 1873. Leprosy is still one of the infectious diseases and major health problem of developing countries. Leprosy is caused by Mycobacterium leprae, M. leprae is pleomorphic, straight or slightly curved, rod shaped gram positive bacteria. It is strong acid fast bacilli and occur in the human host intracellularly. The present case control study was carried out with aim to study the suspected cases of indeterminate leprosy in clinically diagnosed patients in out patients department (OPD) of Gandhi memorial and associated hospitals. Department of Medicine at King George’s Medical College, Lucknow. Study group consisting of 75 cases of indeterminate leprosy, 100 subjects of other groups of leprosy spectrum, i.e., tuberculoid leprosy to lepromatous leprosy (TT - LL), taken as disease control in this study. This study emphasizes the importance of performing histopathological examinations on leprosy patients undergoing research studies for the confirmation of diagnosis and for proper classification of the diagnosis. The study help in effective use of the clinical and histopathological methods in finding out the indeterminate leprosy.