The systematic accounts of striped chest sisorid catfishes of Manipur are given in this paper. Glyptothorax chavomensis, a new species is described from the Chindwin basin of Manipur and can distinguished from its congeners in having the following characters: tubercles consisting of elongate ridges particularly prominent on dorsal surface of head; 5-7 and 2-3 dorso-neural spines in between the inter-dorsal and post-adipose to the origin of procurrent rays of caudal-fin; 10-12 horizontally linear tile like ridges from the latero-posterior end of anus onto the last origin of anal-fin ray; head depth at occiput 70.1-76.8%HL; inter-orbital width 27.9-33.6%HL; internarial width 19.2-19.3%HL; thoracic adhesive apparatus length 69.6-71.6%HL; body depth at anus 17.0-18.2%SL and at dorsal-fin origin 22.2-22.8%SL; dorsal-fin length 18.6-19.0%SL; adipose-fin length 15.6-16.3%SL and dorsal-fin spine length 13.2-14.3%SL.