The study reveals that the socio-economic conditions of the fishermen community in selected areas in the Nizampatnam Guntur district, Andhra Pradesh. The results indicated that the living conditions are very miserable. In most of the families, there are more than four members and among them majority are illiterate. Their dietary requirement is not at all up to the mark, as they do not consume required nutritious food, in turn their physical capacity does not allow them for frequent and regular fish catch. In addition, 86% of people usually get addicted to drinking and smoking habits (liquor and tobacco). They do not have proper drinking water facility. Children of this community suffer from diseases like malaria typhoid, helminthasis, and malnutrition, which lead to gastrointestinal disorders. Measures to be taken to improve the living conditions are integration of agricultural with fish/prawn farming system. Therefore proper fishery management policies, effective input supply, technical, and social support may improve the livelihood of the fishers, which will ultimately increase the overall fisheries productivity of Andhra Pradesh as well as India.