Vol. 3, Issue 4 (2018)
Antibacterial and mosquitocidal potentials of selected Indian medicinal plants extracts and synthesized silver nanoparticles
Author(s): K Krishnappa, J Pandiyan, J Paramanandham, K Elumalai
Abstract: In the present study, the antibacterial and mosquitocidal activity of different leaf extracts and silver nanoparticles (SNPs) of Bridelia montana and Litsea chinensis Indian medicinal plants were analyzed through the zone of inhibition, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) assays against Gram-positive and Gram-negative bacteria and larvicidal activity of fourth instar larvae of selected human vector mosquitoes. Antibacterial activity of zone of inhibition, MIC and MBC of B. montana and L. chinensis extracts tested, the methanol extract showed significant activity against the selected bacteria. Moreover, SNPs of both plants showed maximum zone of inhibition, MIC and MBC in among the human pathogenic bacteria. The Larvicidal potential of medicinal plants different extracts tested, methanol extracts provided significant activity. Besides, the larvicidal properties of SNPs provided highest activity and more than 90% of activity recorded at 25µg/mL concentration. Preliminary phytochemical screenings of extracts were observed that the maximum groups of phytochemicals were present in high polar solvents, especially in methanol extracts. In this study we evaluated the antibacterial and mosquitocidal properties of two Indian medicinal plants extracts and SNPs displayed the potential activity which could be a good source for the alternative of synthetic chemical.