Vol. 2, Issue 6 (2017)
Indian gooseberry and Lycopodium 200c can effectively reduce cadmium induced testicular damage in 40 days exposed mice
Author(s): Mahasweta Chatterjee, Gobinda Chandra Sadhukhan, Jayanta Kumar Kundu
Abstract: Being a potential toxic metal cadmium is known to cause testicular damage by producing reactive oxygen species (ROS) resulting in infertility among male. The cadmium toxicity is due to its accumulation in different mammalian organs through food and drink from the environment. Its removal is not possible by most chelating agents as they are unable to pass through membrane. The present study was undertaken to see the effect of cadmium on mice testes and its remedies by herbal extracts and homeopathic medicines. Among different herbal products, Indian Gooseberry (amla) and the homeopathis medicine Lycopodium 200c are found to have antioxidant, anti-toxic and anti-tumorigenic properties. The study was designed to see the protective role of amla and Lycopodium 200c on cadmium induced testicular damage. To conduct this study, Swiss albino mice were divided into different sets with one control, one induced and other with treatments. Tests for sperm head anomalies (SHA), comet asaay and histopathological analysis of mice testes were performed. Result shows that toxicity and damages caused by cadmium can be effectively reduced with amla extracts and Lycopodium 200c.
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