Effect of nicotine on external morphology, liver and body weight of Oryctolagus cuniculus
Sundus Zahid, Aqeel Hamid
Effect of nicotine on external morphology, liver and body weight of rabbit (Oryctolagus cuniculus) was investigated. Animals were divided into controlled and treated group. One group was kept on normal diet and other was treated with nicotine by 4 different methods i.e. tea, smoke, intra muscular injection and vegetable sprinkle. In between each treatment animals have two weeks of washout time. All animals were kept at 22 0C and 30-40% humidity. Body weight was recorded before and after each treatment and noted huge weight loss (1185 grams) in nicotine treated group. Nicotine also affected the hair coat and loss of hair found and patchy skin was seen compared to controlled animals. At the end of liver color and weight was recorded which was light brown in treated and dark maroon in controlled group. Liver weight almost 20% was lost in nicotine treated group. Eyes were affected too showing muscular and nervous deteriorating. These results shows deteriorating effect of the nicotine on morphology weight of the animals and their organs most importantly on liver.